The majority of dietary supplements have never been tested in human clinical trials on the actual product.

DS-01® has been tested in multiple full formulation randomized, placebo-controlled clinical trials, including the largest probiotic clinical trial evaluating bloating, in otherwise healthy women and men.

In addition, DS-01®’s ingredients have been validated in clinical trials to assess benefits in and beyond the gut.

The Impact of Clinical Proof

Randomized, placebo-controlled trials provide clarity and bring rigor to scientific research for various reasons, including:

• Eliminate bias
• Rule out placebo-effect
• Establish causality
• Validate efficacy

By testing DS-01® as a full formulation, the entire product is validated for tolerability and efficacy.

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In Seed’s largest clinical trial on DS-01, 350 men and women were evaluated using clinically-validated GI endpoints in partnership with leading gastroenterology physicians and academic microbiome researchers. This study shows real-world relevance with participants from 40 states and territories, reflecting the broader US population.

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Bloating + Gas Relief* 

• DS-01 resulted in a significant reduction in bloating and gas symptoms compared to placebo.

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Improvement in Regularity* 

• DS-01 improved bowel habits, specifically addressing occasional constipation-related discomfort, stool quality, and supporting regularity compared to placebo.

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Reduced GI Discomfort* 

• DS-01 led to a reduction in abdominal discomfort compared to placebo. 

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Improved Quality of Life *

• DS-01 improved GI-related quality of life compared to placebo. This included greater food enjoyment, reduced food avoidance, and significantly less disruption of physical activity due to digestive events